한국지질동맥경화학회 학술대회

Premature atherosclerosis, marked by the early onset of atherosclerotic cardiovascular disease (ASCVD), is a growing global concern. Understanding its risk factors is essential for developing effective prevention and treatment strategies. This joint session will explore the background, risk factors, and latest research findings on premature atherosclerosis across different regions. Professor Ashraf Reda from Menoufia University (current President of the Egyptian Association of Vascular Biology and Atherosclerosis) will present findings from Egyptian data, providing insights into the prevalence and characteristics of premature atherosclerosis in this region. Professor EL Sayed Farag from Zagazig University will discuss archived case scenarios, highlighting unique cases and outcomes that shed light on the clinical manifestations and progression of this condition. Professor Su-Yeon Choi from Seoul National University will examine metabolic risk factors and their association with ASCVD in young Korean adults, offering a comparative perspective and potential preventive strategies.

This session, titled "Recent advances in metaflammation and atherosclerosis research," will introduce the latest researches in metaflammation and atherosclerosis. Professor Takehiko Yokomizo from Juntendo University will present protective roles of BLT2 receptor on the plasma membrane disruption-induced epithelial cell damage. Professor Mahmoud Abdellatif from the University of Graz will present on the cardioprotective mechanisms of the SGLT2 inhibitor, empagliflozin in myocardial infarction. Professor Yun-Hee Lee from the College of Pharmacy at Seoul National University will discuss TM4SF19-mediated lysosomal activity of macrophages in metaflammation, providing insights into macrophage function in metabolic inflammation. This session promises to offer valuable knowledge on the latest research trends and their practical applications in the field.

This session will focus on comprehensive cardiac rehabilitation for patients with atherosclerotic cardiovascular disease. We will cover the effectiveness and safety of exercise therapy, dietary control, and cardiac rehabilitation programs for secondary prevention in patients with myocardial infarction, angina, stroke, and peripheral arterial disease. Beyond general exercise and dietary recommendations, Professor Ick-Mo Chung from Ewha Womans University (current President of the Korean Society of Lipid and Atherosclerosis) will discuss the significance and necessity of cardiac rehabilitation, Professor Randal J. Thomas from Mayo Clinic will present the latest insights and applications of cardiac rehabilitation program, Professor Qi Sun from Harvard Medical School will cover nutritional management strategies for cardiometabolic diseases, and Professor Kyuwan Lee from Ewha Womans University will share key insights on exercise therapy for patients with diabetes and cardiovascular disease.

This session is a joint symposium organized by the Australian Atherosclerosis Society (MS) and the Korean Society of Lipid and Atherosclerosis (KSoLA), focusing on vascular abnormalities related to diabetes. The session will feature presentations by three distinguished professors on different topics. First, Professor Judy de Haan from the Baker Heart and Diabetes Institute in Australia will give a lecture on "Targeting Inflammation to lessen diabetes-associated cardiovascular complications." This presentation will cover strategies for controlling inflammation to improve cardiovascular health in diabetic patients. The second speaker is Professor Jae-Han Jeon from Kyungpook National University in Korea, who will present on "Diabetic Nephropathy and Endothelial Dysfunction." This presentation will delve into the kidney diseases caused by diabetes and the changes in endothelial cell function associated with it. Lastly, Professor Georges Grau from the University of Sydney in Australia will present an intriguing case study on "Vascular dysfunction in cerebral malaria: a peculiar case of immuno-thrombosis, underpinned by extracellular vesicles," focusing on immunopathology related to extracellular vesicles. This presentation will explore vascular changes in the brain during malaria infection, discussing the related immune responses and pathological mechanisms. We hope this session will provide an opportunity to explore and discuss various vascular abnormalities in diabetes.

Recently, there has been a surge in efforts to find solutions to metabolic disease treatment strategies from adipose tissue biology, such as systematically establishing the hallmarks of adipose tissue dysfunction in the development of metabolic diseases. This session will focus on the latest research on the biological functions of adipose tissue and adipocytes, conducted from various perspectives. Professor Jae Myoung Suh from KAIST will present a study on new regulatory mechanisms of fuel metabolism in adipose tissue from RNA biology perspective. Professor Motoharu Awazawa from National Center for Global Health and Medicine (NCGM) will discuss the effects of new antidiabetic drugs on system-level metabolic physiology including adipose tissues. Professor Kae Won Cho from Soonchunhyang University (SIMS) will discuss the new pathophysiological roles of adipose dendritic cells in metabolic diseases.

This joint session is organized for academic exchange between the Korean Society of Lipid and Atherosclerosis (KSoLA) and the Society for Heart and Vascular Metabolism (SHVM). The first speaker, Professor Tae-Sik Park from Gachon University, will present on the role and regulatory mechanisms of S1P, a bioactive Iipid mediator and a sphingolipid metabolite, in NASH, based on his years of research. The second speaker, Professor Linda Peterson from Washington University, will discuss her research achievements on the role of ceramide, another sphingolipid metabolite, in cardiovascular diseases. The final speaker, Professor Helen E. Collins from the University of Louisville, will address the mechanisms of cardiac changes during pregnancy, a somewhat different topic. We hope that this session will help in understanding new risk factors and mechanisms in various diseases and physiological changes.